Kisters K1,6, Gremmler B1, Hunger R2, Tokmak F3, Nguyen MQ4, Hausberg M5, Gröber U6
There is still increasing importance of ionized magnesium concentrations in a variety of human diseases. A magnesium loss can be involved in cardiovascular diseases, e.g. arterial hypertension, heart insufficiency, arrhythmias, arteriosclerosis or diabetes mellitus. Plasma or serum magnesium content constitues about 3–5 % of total body magnesium stores. Ionized magnesium is about 50 % in blood and the active form of magnesium.
For measuring ionized magnesium a new apparatus pHOx + M, NOVA, Rödermark, Germany is used, a specialized blood gas analyzer.
From earlier studies it is well documented that there is a good correlation between total blood/serum and ionized magnesium concentrations.
Especially determination of ionized magnesium in cardiovascular diseases and in sports or stress are of importance. In each case a magnesium loss has to be corrected sufficiently to avoid further disease.
K. Kisters, B. Gremmler, U. Gröber, M. Hausberg. Ionized magnesium loss in hypertension and diabetes mellitus. J Hypertens 33, e-Suppl. 1, e 436, 2015